Q75* (p.Gln75Ter) variant of PRNP (Major prion protein)
Q75* (p.Gln75Ter) in PRNP (Major prion protein) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.83 / 1. The record also includes population frequency data and structural context.
Q75* (p.Gln75Ter) variant details
- p.Gln75Ter
- ExAC rs753810713
- TOPMed rs753810713
- gnomAD rs753810713
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.825
- CADD 35.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available