P68P (p.Pro68Pro) variant of PRNP (Major prion protein)
P68P (p.Pro68Pro) in PRNP (Major prion protein) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, published literature, and structural context.
P68P (p.Pro68Pro) variant details
- p.Pro68Pro
- rs532493114
- gnomAD 20-4699424-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.0886
- CADD 1.13
- Most common in the HGDP:YORUBA population (allele frequency 0.048)
- Structural context available
- Literature evidence available