P26R (p.Pro26Arg) variant of PRNP (Major prion protein)
P26R (p.Pro26Arg) in PRNP (Major prion protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
P26R (p.Pro26Arg) variant details
- p.Pro26Arg
- TOPMed rs1922378268
- gnomAD rs1922378268
- Missense
- Variant Prioritization Score for Impact Estimate 0.53
- REVEL 0.48
- CADD 24.40
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available