N3K (p.Asn3Lys) variant of PRNP (Major prion protein)
N3K (p.Asn3Lys) in PRNP (Major prion protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
N3K (p.Asn3Lys) variant details
- p.Asn3Lys
- TOPMed rs1922369989
- Missense
- Variant Prioritization Score for Impact Estimate 0.244
- REVEL 0.08
- CADD 1.01
- PolyPhen-2 0.15
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available