L19L (p.Leu19Leu) variant of PRNP (Major prion protein)
L19L (p.Leu19Leu) in PRNP (Major prion protein) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, published literature, and structural context.
L19L (p.Leu19Leu) variant details
- p.Leu19Leu
- rs1261971734
- gnomAD 20-4699275-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.0856
- CADD 0.70
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available
- Literature evidence available