K24K (p.Lys24Lys) variant of PRNP (Major prion protein)
K24K (p.Lys24Lys) in PRNP (Major prion protein) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
K24K (p.Lys24Lys) variant details
- p.Lys24Lys
- rs1922376980
- gnomAD 20-4699292-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.38
- CADD 9.43
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available