G74G (p.Gly74Gly) variant of PRNP (Major prion protein)
G74G (p.Gly74Gly) in PRNP (Major prion protein) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
G74G (p.Gly74Gly) variant details
- p.Gly74Gly
- rs766136217
- gnomAD 20-4699442-G-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.081
- CADD 0.04
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available
- Literature evidence available