G5G (p.Gly5Gly) variant of PRNP (Major prion protein)
G5G (p.Gly5Gly) in PRNP (Major prion protein) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data, published literature, and structural context.
G5G (p.Gly5Gly) variant details
- p.Gly5Gly
- gnomAD 20-4699235-C-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.559
- CADD 8.81
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available