G53G (p.Gly53Gly) variant of PRNP (Major prion protein)
G53G (p.Gly53Gly) in PRNP (Major prion protein) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, published literature, and structural context.
G53G (p.Gly53Gly) variant details
- p.Gly53Gly
- rs776188950
- gnomAD 20-4699379-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.0879
- CADD 1.02
- Most common in the HGDP:HAZARA population (allele frequency 0.031)
- Structural context available
- Literature evidence available