G46G (p.Gly46Gly) variant of PRNP (Major prion protein)
G46G (p.Gly46Gly) in PRNP (Major prion protein) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
G46G (p.Gly46Gly) variant details
- p.Gly46Gly
- gnomAD 20-4699358-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.32
- CADD 11.90
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available