V158L (p.Val158Leu) variant of PRMT5 (O14744)
V158L (p.Val158Leu) in PRMT5 (O14744) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
V158L (p.Val158Leu) variant details
- p.Val158Leu
- TOPMed rs1301983404
- gnomAD rs1301983404
- Missense
- Variant Prioritization Score for Impact Estimate 0.337
- REVEL 0.07
- CADD 19.10
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available