T67I (p.Thr67Ile) variant of PRMT5 (O14744)
T67I (p.Thr67Ile) in PRMT5 (O14744) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
T67I (p.Thr67Ile) variant details
- p.Thr67Ile
- gnomAD rs1454266934
- Missense
- Variant Prioritization Score for Impact Estimate 0.525
- REVEL 0.32
- CADD 28.60
- PolyPhen-2 0.91
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available