T29I (p.Thr29Ile) variant of PRMT5 (O14744)
T29I (p.Thr29Ile) in PRMT5 (O14744) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
T29I (p.Thr29Ile) variant details
- p.Thr29Ile
- gnomAD rs1364736472
- Missense
- Variant Prioritization Score for Impact Estimate 0.439
- REVEL 0.22
- CADD 23.70
- PolyPhen-2 0.05
- SIFT 0.12
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available