T139S (p.Thr139Ser) variant of PRMT5 (O14744)
T139S (p.Thr139Ser) in PRMT5 (O14744) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
T139S (p.Thr139Ser) variant details
- p.Thr139Ser
- TOPMed rs1313292314
- gnomAD rs1313292314
- Missense
- Variant Prioritization Score for Impact Estimate 0.44
- REVEL 0.25
- CADD 19.50
- PolyPhen-2 0.00
- SIFT 0.41
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available