T139P (p.Thr139Pro) variant of PRMT5 (O14744)
T139P (p.Thr139Pro) in PRMT5 (O14744) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
T139P (p.Thr139Pro) variant details
- p.Thr139Pro
- Ensembl rs1594520952
- Missense
- Variant Prioritization Score for Impact Estimate 0.345
- REVEL 0.16
- CADD 22.70
- PolyPhen-2 0.12
- SIFT 0.20
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available