S74P (p.Ser74Pro) variant of PRMT5 (O14744)
S74P (p.Ser74Pro) in PRMT5 (O14744) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
S74P (p.Ser74Pro) variant details
- p.Ser74Pro
- TOPMed rs1338803253
- gnomAD rs1338803253
- Missense
- Variant Prioritization Score for Impact Estimate 0.375
- REVEL 0.20
- CADD 23.60
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available