R91C (p.Arg91Cys) variant of PRMT5 (O14744)
R91C (p.Arg91Cys) in PRMT5 (O14744) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
R91C (p.Arg91Cys) variant details
- p.Arg91Cys
- ExAC rs765221574
- gnomAD rs765221574
- Missense
- Variant Prioritization Score for Impact Estimate 0.399
- REVEL 0.14
- CADD 26.20
- PolyPhen-2 0.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available