P24R (p.Pro24Arg) variant of PRMT5 (O14744)
P24R (p.Pro24Arg) in PRMT5 (O14744) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
P24R (p.Pro24Arg) variant details
- p.Pro24Arg
- ExAC rs763450079
- gnomAD rs763450079
- Missense
- Variant Prioritization Score for Impact Estimate 0.571
- REVEL 0.46
- CADD 23.50
- PolyPhen-2 0.03
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available