P156H (p.Pro156His) variant of PRMT5 (O14744)
P156H (p.Pro156His) in PRMT5 (O14744) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data and structural context.
P156H (p.Pro156His) variant details
- p.Pro156His
- ExAC rs774009994
- gnomAD rs774009994
- Missense
- Variant Prioritization Score for Impact Estimate 0.814
- REVEL 0.82
- CADD 29.20
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available