M153V (p.Met153Val) variant of PRMT5 (O14744)
M153V (p.Met153Val) in PRMT5 (O14744) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
M153V (p.Met153Val) variant details
- p.Met153Val
- TOPMed rs2044430964
- Missense
- Variant Prioritization Score for Impact Estimate 0.287
- REVEL 0.06
- CADD 22.60
- PolyPhen-2 0.00
- SIFT 0.58
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available