M153T (p.Met153Thr) variant of PRMT5 (O14744)
M153T (p.Met153Thr) in PRMT5 (O14744) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
M153T (p.Met153Thr) variant details
- p.Met153Thr
- ExAC rs767903559
- gnomAD rs767903559
- Missense
- Variant Prioritization Score for Impact Estimate 0.326
- REVEL 0.13
- CADD 23.70
- PolyPhen-2 0.03
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available