M150V (p.Met150Val) variant of PRMT5 (O14744)
M150V (p.Met150Val) in PRMT5 (O14744) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
M150V (p.Met150Val) variant details
- p.Met150Val
- ExAC rs778358225
- gnomAD rs778358225
- Missense
- Variant Prioritization Score for Impact Estimate 0.348
- REVEL 0.17
- CADD 22.80
- PolyPhen-2 0.00
- SIFT 0.33
- Most common in the REMAINING population (allele frequency 3.3e-05)
- Structural context available