M150T (p.Met150Thr) variant of PRMT5 (O14744)
M150T (p.Met150Thr) in PRMT5 (O14744) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
M150T (p.Met150Thr) variant details
- p.Met150Thr
- ExAC rs770437054
- TOPMed rs770437054
- gnomAD rs770437054
- Missense
- Variant Prioritization Score for Impact Estimate 0.502
- REVEL 0.44
- CADD 22.50
- PolyPhen-2 0.00
- SIFT 0.22
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available