M107V (p.Met107Val) variant of PRMT5 (O14744)
M107V (p.Met107Val) in PRMT5 (O14744) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
M107V (p.Met107Val) variant details
- p.Met107Val
- TOPMed rs888016418
- gnomAD rs888016418
- Missense
- Variant Prioritization Score for Impact Estimate 0.328
- REVEL 0.14
- CADD 22.70
- PolyPhen-2 0.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available