K98M (p.Lys98Met) variant of PRMT5 (O14744)
K98M (p.Lys98Met) in PRMT5 (O14744) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
K98M (p.Lys98Met) variant details
- p.Lys98Met
- gnomAD rs1193649482
- Missense
- Variant Prioritization Score for Impact Estimate 0.216
- REVEL 0.05
- CADD 22.50
- PolyPhen-2 0.05
- SIFT 0.25
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available