K35R (p.Lys35Arg) variant of PRMT5 (O14744)
K35R (p.Lys35Arg) in PRMT5 (O14744) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
K35R (p.Lys35Arg) variant details
- p.Lys35Arg
- ExAC rs772180370
- gnomAD rs772180370
- Missense
- Variant Prioritization Score for Impact Estimate 0.267
- REVEL 0.09
- CADD 23.10
- PolyPhen-2 0.00
- SIFT 0.45
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available