G8D (p.Gly8Asp) variant of PRMT5 (O14744)
G8D (p.Gly8Asp) in PRMT5 (O14744) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
G8D (p.Gly8Asp) variant details
- p.Gly8Asp
- 1000Genomes rs201479952
- ExAC rs201479952
- TOPMed rs201479952
- gnomAD rs201479952
- Missense
- Variant Prioritization Score for Impact Estimate 0.201
- REVEL 0.13
- CADD 15.90
- PolyPhen-2 0.02
- SIFT 0.61
- Most common in the 1KG:TSI population (allele frequency 0.0049)
- Structural context available