G8A (p.Gly8Ala) variant of PRMT5 (O14744)
G8A (p.Gly8Ala) in PRMT5 (O14744) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
G8A (p.Gly8Ala) variant details
- p.Gly8Ala
- 1000Genomes rs201479952
- ExAC rs201479952
- TOPMed rs201479952
- gnomAD rs201479952
- Missense
- Variant Prioritization Score for Impact Estimate 0.196
- REVEL 0.13
- CADD 14.30
- PolyPhen-2 0.00
- SIFT 0.67
- Most common in the 1KG:GWD population (allele frequency 0.0043)
- Structural context available