G84V (p.Gly84Val) variant of PRMT5 (O14744)
G84V (p.Gly84Val) in PRMT5 (O14744) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.71 / 1. The record also includes population frequency data and structural context.
G84V (p.Gly84Val) variant details
- p.Gly84Val
- ExAC rs779549081
- gnomAD rs779549081
- Missense
- Variant Prioritization Score for Impact Estimate 0.713
- REVEL 0.64
- CADD 29.00
- PolyPhen-2 0.90
- SIFT 0.01
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available