G84A (p.Gly84Ala) variant of PRMT5 (O14744)
G84A (p.Gly84Ala) in PRMT5 (O14744) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
G84A (p.Gly84Ala) variant details
- p.Gly84Ala
- ExAC rs779549081
- gnomAD rs779549081
- Missense
- Variant Prioritization Score for Impact Estimate 0.496
- REVEL 0.32
- CADD 22.60
- PolyPhen-2 0.18
- SIFT 0.13
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available