G31E (p.Gly31Glu) variant of PRMT5 (O14744)
G31E (p.Gly31Glu) in PRMT5 (O14744) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
G31E (p.Gly31Glu) variant details
- p.Gly31Glu
- ExAC rs775567375
- gnomAD rs775567375
- Missense
- Variant Prioritization Score for Impact Estimate 0.42
- REVEL 0.19
- CADD 22.30
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available