G11E (p.Gly11Glu) variant of PRMT5 (O14744)
G11E (p.Gly11Glu) in PRMT5 (O14744) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
G11E (p.Gly11Glu) variant details
- p.Gly11Glu
- ExAC rs758730512
- gnomAD rs758730512
- Missense
- Variant Prioritization Score for Impact Estimate 0.417
- REVEL 0.25
- CADD 22.90
- PolyPhen-2 0.01
- SIFT 0.82
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available