G10A (p.Gly10Ala) variant of PRMT5 (O14744)
G10A (p.Gly10Ala) in PRMT5 (O14744) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
G10A (p.Gly10Ala) variant details
- p.Gly10Ala
- gnomAD rs1464180555
- Missense
- Variant Prioritization Score for Impact Estimate 0.384
- REVEL 0.13
- CADD 22.70
- PolyPhen-2 0.00
- SIFT 0.82
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available