E161D (p.Glu161Asp) variant of PRMT5 (O14744)
E161D (p.Glu161Asp) in PRMT5 (O14744) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
E161D (p.Glu161Asp) variant details
- p.Glu161Asp
- ExAC rs201206132
- gnomAD rs201206132
- Missense
- Variant Prioritization Score for Impact Estimate 0.229
- REVEL 0.22
- CADD 13.90
- PolyPhen-2 0.00
- SIFT 0.40
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00047)
- Structural context available