D93A (p.Asp93Ala) variant of PRMT5 (O14744)
D93A (p.Asp93Ala) in PRMT5 (O14744) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and structural context.
D93A (p.Asp93Ala) variant details
- p.Asp93Ala
- ExAC rs753685975
- gnomAD rs753685975
- Missense
- Variant Prioritization Score for Impact Estimate 0.641
- REVEL 0.62
- CADD 28.80
- PolyPhen-2 0.91
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available