D77N (p.Asp77Asn) variant of PRMT5 (O14744)
D77N (p.Asp77Asn) in PRMT5 (O14744) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
D77N (p.Asp77Asn) variant details
- p.Asp77Asn
- Ensembl rs2044476149
- Missense
- Variant Prioritization Score for Impact Estimate 0.451
- REVEL 0.15
- CADD 35.00
- PolyPhen-2 0.88
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available