D19N (p.Asp19Asn) variant of PRMT5 (O14744)
D19N (p.Asp19Asn) in PRMT5 (O14744) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
D19N (p.Asp19Asn) variant details
- p.Asp19Asn
- TOPMed rs969813856
- Missense
- Variant Prioritization Score for Impact Estimate 0.41
- REVEL 0.13
- CADD 25.80
- PolyPhen-2 1.00
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available