A32T (p.Ala32Thr) variant of PRMT5 (O14744)
A32T (p.Ala32Thr) in PRMT5 (O14744) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
A32T (p.Ala32Thr) variant details
- p.Ala32Thr
- gnomAD rs1345690985
- Missense
- Variant Prioritization Score for Impact Estimate 0.356
- REVEL 0.15
- CADD 23.10
- PolyPhen-2 0.00
- SIFT 0.48
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available