A32S (p.Ala32Ser) variant of PRMT5 (O14744)
A32S (p.Ala32Ser) in PRMT5 (O14744) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
A32S (p.Ala32Ser) variant details
- p.Ala32Ser
- gnomAD rs1345690985
- Missense
- Variant Prioritization Score for Impact Estimate 0.41
- REVEL 0.24
- CADD 23.00
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available