A27S (p.Ala27Ser) variant of PRMT5 (O14744)
A27S (p.Ala27Ser) in PRMT5 (O14744) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
A27S (p.Ala27Ser) variant details
- p.Ala27Ser
- gnomAD rs2044497213
- Missense
- Variant Prioritization Score for Impact Estimate 0.378
- REVEL 0.12
- CADD 21.70
- PolyPhen-2 0.00
- SIFT 0.76
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available