A115T (p.Ala115Thr) variant of PRMT5 (O14744)
A115T (p.Ala115Thr) in PRMT5 (O14744) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
A115T (p.Ala115Thr) variant details
- p.Ala115Thr
- gnomAD rs1188199418
- Missense
- Variant Prioritization Score for Impact Estimate 0.411
- REVEL 0.17
- CADD 23.00
- PolyPhen-2 0.23
- SIFT 0.18
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available