A105V (p.Ala105Val) variant of PRMT5 (O14744)
A105V (p.Ala105Val) in PRMT5 (O14744) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
A105V (p.Ala105Val) variant details
- p.Ala105Val
- ExAC rs199877231
- TOPMed rs199877231
- gnomAD rs199877231
- Missense
- Variant Prioritization Score for Impact Estimate 0.286
- REVEL 0.11
- CADD 23.40
- PolyPhen-2 0.01
- SIFT 0.56
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available