L4L (p.Leu4Leu) variant of PRKG1 (cGMP-dependent protein kinase 1)
L4L (p.Leu4Leu) in PRKG1 (cGMP-dependent protein kinase 1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
L4L (p.Leu4Leu) variant details
- p.Leu4Leu
- gnomAD 10-50991388-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.313
- CADD 13.80
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available
- Literature evidence available