K15E (p.Lys15Glu) variant of PRKG1 (cGMP-dependent protein kinase 1)
K15E (p.Lys15Glu) in PRKG1 (cGMP-dependent protein kinase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data, published literature, and structural context.
K15E (p.Lys15Glu) variant details
- p.Lys15Glu
- gnomAD 10-50991421-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.58
- MetaLR 0.49
- MetaSVM 0.17
- CADD 26.00
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available