I33M (p.Ile33Met) variant of PRKG1 (cGMP-dependent protein kinase 1)
I33M (p.Ile33Met) in PRKG1 (cGMP-dependent protein kinase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
I33M (p.Ile33Met) variant details
- p.Ile33Met
- ExAC rs766478650
- TOPMed rs766478650
- gnomAD rs766478650
- Missense
- Variant Prioritization Score for Impact Estimate 0.359
- MetaLR 0.32
- MetaSVM -0.52
- CADD 22.50
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)
- Structural context available