T11K (p.Thr11Lys) variant of PRKCA (Protein kinase C alpha type)
T11K (p.Thr11Lys) in PRKCA (Protein kinase C alpha type) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
T11K (p.Thr11Lys) variant details
- p.Thr11Lys
- gnomAD 17-66302883-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.167
- REVEL 0.08
- CADD 18.70
- PolyPhen-2 0.04
- SIFT 0.48
- Population evidence available
- Structural context available
- Literature evidence available