R19C (p.Arg19Cys) variant of PRKCA (Protein kinase C alpha type)
R19C (p.Arg19Cys) in PRKCA (Protein kinase C alpha type) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
R19C (p.Arg19Cys) variant details
- p.Arg19Cys
- gnomAD 17-66302906-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.385
- REVEL 0.41
- CADD 27.40
- PolyPhen-2 0.70
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available