K62R (p.Lys62Arg) variant of PRKCA (Protein kinase C alpha type)
K62R (p.Lys62Arg) in PRKCA (Protein kinase C alpha type) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data, published literature, and structural context.
K62R (p.Lys62Arg) variant details
- p.Lys62Arg
- gnomAD 17-66306107-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.539
- REVEL 0.50
- CADD 24.50
- PolyPhen-2 0.05
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available