K35R (p.Lys35Arg) variant of PRKCA (Protein kinase C alpha type)
K35R (p.Lys35Arg) in PRKCA (Protein kinase C alpha type) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
K35R (p.Lys35Arg) variant details
- p.Lys35Arg
- gnomAD 17-66302955-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.39
- REVEL 0.27
- CADD 24.40
- PolyPhen-2 0.03
- SIFT 0.10
- Population evidence available
- Structural context available
- Literature evidence available