K23R (p.Lys23Arg) variant of PRKCA (Protein kinase C alpha type)
K23R (p.Lys23Arg) in PRKCA (Protein kinase C alpha type) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
K23R (p.Lys23Arg) variant details
- p.Lys23Arg
- gnomAD rs1261479202
- Missense
- Variant Prioritization Score for Impact Estimate 0.43
- REVEL 0.20
- CADD 22.10
- PolyPhen-2 0.00
- SIFT 0.75
- Population evidence available
- Structural context available